Charity Parkinson's UK has awarded a grant of nearly £35,000 to Dr Cathy Craig of Queen's University Belfast to see whether it can improve physical abilities and improve symptoms.
In a poll, 81% of people with Parkinson's said that they would use Wii Fit regularly for exercise, and 68% said that it would help to manage their symptoms.
Earlier today Mirren, who has a friend with the disease, revealed that the potential benefits were the reason she chose to promote the Wii in recent television adverts.
Mirren was reportedly paid £500,000 to feature in the advert.